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GB11379-1 Anti -Mineralocorticoid receptor Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11379-1
  • Servicebio

Description

Product Information


Description

Mineralocorticoid receptor rabbit polyclonal

Protein full name

Mineralocorticoid receptor

Synonyms

NR3C2, MCR, MLR, MR, NR3C2VIT, nuclear receptor subfamily 3 group C member 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

Q8VII8, P08235, P22199




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human,

Mouse, Rat

1: 500-1: 1000

stomach, brain, heart, liver, kidney

IF

Human,

Mouse, Rat

1: 500-1: 1000

stomach, brain, heart, liver, kidney




Background


Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.



Images



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Immunohistochemistry analysis of paraffin-embedded human stomach using Mineralocorticoid receptor (GB11379-1) at dilution of 1: 750

image.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using Mineralocorticoid receptor (GB11379-1) at dilution of 1: 750

image.png

Immunohistochemistry analysis of paraffin-embedded rat heart using Mineralocorticoid receptor (GB11379-1) at dilution of 1: 750




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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