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GB11382 Anti -Wilms Tumor Protein Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse WT1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11382
  • Servicebio

Description

Product Information


Description

Wilms Tumor Protein rabbit polyclonal

Protein full name

Wilms tumor protein homolog

Synonyms

AEWS-GUD, NPHS4, WAGR, WIT-2, WT33, Wilms tumor, WT1

Immunogen

Recombinant protein corresponding to Mouse WT1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P22561, P49952, P19544




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 100-1: 300

kidney

IF

Human, Mouse, Rat

1: 100-1: 300

kidney




Background


Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (By similarity). Regulates the expression of numerous target genes, including EPO . Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing . Isoform 1 has lower affinity for DNA, and can bind RNA.



Images



image.png

Immunohistochemistry analysis of paraffin-embedded human kidney using WT1 (GB11382) at dilution of 1: 200

image.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using WT1 (GB11382) at dilution of 1: 200

image.png

Immunohistochemistry analysis of paraffin-embedded rat kidney using WT1 (GB11382) at dilution of 1: 200




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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