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GB11392 Anti -PKM2 Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse PKM2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11392
  • Servicebio

Description

Product Information


Description

PKM2 rabbit polyclonal

Protein full name

Pyruvate kinase PKM

Synonyms

PKM, CTHBP, HEL-S-30, OIP3, PK3, PKM2, TCB, THBP1, pyruvate kinase, muscle

Immunogen

Recombinant protein corresponding to Mouse PKM2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

58 kDa

Observed MW.

58 kDa

Uniprot ID

P52480, P14618, P11980




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

muscle, brain




Background


Pyruvate kinase isozymes M1/M2 (PKM1/M2), also known as pyruvate kinase muscle isozyme (PKM), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting protein 3 (OIP3), is an enzyme that in humans is encoded by the PKM2 gene.Pyruvate kinase catalyzes the last step within glycolysis, the dephosphorylation of phosphoenolpyruvate to pyruvate, and is responsible for net ATP production within the glycolytic sequence. In contrast to mitochondrial respiration, energy regeneration by pyruvate kinase is independent from oxygen supply and allows survival of the organs under hypoxic conditions often found in solid tumors.




Images



GB11392.png

Western blot analysis of PKM2 (GB11392) at dilution of 1:1000.

Lane 1:HepG2 cell lysate

Lane 2:A549 cell lysate

Lane 3:SH-SY5Y cell lysate

Lane 4:Mouse muscle tissue lysate

Lane 5:Mouse brain tissue lysate

Lane 6:Rat muscle tissue lysate

Lane 7:Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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