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GB11405 Anti -mTOR Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to  Mouse mTOR
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11405
  • Servicebio

Description

Product Information


Description

mTOR rabbit polyclonal

Protein full name

Serine/threonine-protein kinase mTOR

Synonyms

FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR

Immunogen

Recombinant protein corresponding to Mouse mTOR

Isotype

IgG

Purity

Affinity purification

Predicted MW.

289 kDa

Observed MW.

289 kDa

Uniprot ID

P42345, Q9JLN9, P42346




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 1000

testis, liver, brain




Background


Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.

   



Images



GB11405.png

Western blot analysis of mTOR (GB11405) at dilution of 1:1000.

Lane 1:HeLa cell lysate

Lane 2:A431 cell lysate

Lane 3:MCF-7 cell lysate

Lane 4:Mouse testis tissue lysate

Lane 5:Mouse liver tissue lysate

Lane 6:Mouse brain tissue lysate

Lane 7:Rat testis tissue lysate

Lane 8:Rat liver tissue lysate

Lane 9:Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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