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GB11407 Anti -Lamin A+C Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Lamin A + Lamin C
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11407
  • Servicebio

Description

Product Information

Description

Lamin A+C rabbit polyclonal

Protein full name

Prelamin-A/C

Synonyms

LMNA, CDCD1, CDDC, CMD1A, CMT2B1 EMD2, FPL, FPLD, FPLD2, HGPS, IDC LDP1, LFP, LGMD1B, LMN1, LMNC LMNL1, PRO1, lamin A/C, MADA

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Lamin A+C

Isotype

IgG

Purity

Affinity purification

Predicted MW.

74 kDa

Observed MW.

74 kDa

Subcellular location

Nucleus

Uniprot ID

P02545, P48678, P48679




Applications

applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

lung, heart, liver

IHC

Human, Mouse, Rat

1: 500-1: 800

lung, liver

IF

Human, Rat

1: 500-1: 800

ovary, liver




Background

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.




Images


GB11407.png

Western blot analysis of Lamin A+C (GB11407) at dilution of 1: 1000.

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: NIH/3T3 cell lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Mouse heart tissue lysate

Lane 6: Mouse liver tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8: Rat heart tissue lysate

Lane 9: Rat liver tissue lysate

Immunohistochemistry analysis of paraffin-embedded human lung cancer using Lamin A+C (GB11407) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded human liver cancer using Lamin A/C (GB11407) at dilution of 1:500

Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Lamin A/C (GB11407) at dilution of 1:500

Immunohistochemistry analysis of paraffin-embedded mouse liver using Lamin A/C (GB11407)at dilution of 1:800

Immunohistochemistry analysis of paraffin-embedded rat liver using Lamin A/C (GB11407) at dilution of 1:800

Immunofluorescent analysis of paraformaldehyde-fixed human ovary using Lamin A/C (GB11407) at dilution of 1:800

Immunofluorescent analysis of paraformaldehyde-fixed rat liver using Lamin A/C (GB11407) at dilution of 1:800





Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.






NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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