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GB11410 Anti -Dicer Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Dicer
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11410
  • Servicebio

Description

Product Information


Description

Dicer rabbit polyclonal

Protein full name

Endoribonuclease Dicer

Synonyms

DICER1, DCR1, Dicer, Dicer1e, HERNA,

MNG1, RMSE2, K12H4.8-LIKE, dicer 1, ribonuclease III

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Dicer

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

Q9UPY3, Q8R418




Applications


applications

species

dilution

Positive tissue

IHC

Human, Mouse, Rat

1: 1000

brain, kidney

IF

Human, Mouse, Rat

1: 1000

brain, kidney




Background


Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation.




Images



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Immunohistochemistry analysis of paraffin-embedded rat brain using Dicer (GB11410) at dilution of 1:1000

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Immunohistochemistry analysis of paraffin-embedded human kidney using Dicer (GB11410) at dilution of 1:1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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