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GB11500 Anti -Osteopontin Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Osteopontin
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11500
  • Servicebio

Description

Product Information


Description

Osteopontin rabbit polyclonal

Protein full name

Osteopontin

Synonyms

SPP1, BNSP, BSPI, ETA-1, OPN, secreted phosphoprotein 1, Osteopontin

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Osteopontin

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P10923, P08721, P10451




Applications


applications

species

dilution

Positive tissue

IHC

Mouse, Rat

1: 500-1: 1000

bone

IF

Rat

1: 500-1: 1000

brain, substantia nigra




Background


Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a protein that in humans is encoded by theSPP1 gene (secreted phosphoprotein 1).Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine. Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the vitronectin receptor, which has specificity for osteopontin. Osteopontin is overexpressed in a variety of cancers, including lung, breast, colorectal, stomach, ovarian, melanoma and mesothelioma.




Images



Immunohistochemistry analysis of paraffin-embedded mouse bone using Osteopontin (GB11500) at dilution of

1: 1000.

Immunohistochemistry analysis of paraffin-embedded mouse bone using Osteopontin (GB11500) at dilution of 1:1000.

Immunohistochemistry analysis of paraffin-embedded rat bone using Osteopontin (GB11500) at dilution of

1: 1000.

Immunofluorescent analysis of paraformaldehyde-fixed rat brain substantia nigra using Osteopontin (GB11500) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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