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GB11508 Anti -Histone H4 Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to human Histone H4
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11508
  • Servicebio

Description

Product Information


Description

Histone H4 rabbit polyclonal

Protein full name

Histone H4

Synonyms

H4F2, H4FN, HIST1H4, HIST2H4, HISTH4H4, H4c1, Hist1h4a, H4c2, H4-53, Hist1h4b, H4c3, H4-12, Hist1h4c, H4c4, Hist1h4d, Hist1h4f, H4c6, H4c14, Hist2h4, Hist2h4a

Immunogen

Recombinant protein corresponding to human Histone H4

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P62805, P62806




Applications


applications

species

dilution

Positive tissue

IHC

Human

1: 1000

tonsil, lung cancer, liver cancer, colon, colon cancer, lymphoma, breast

IF

Human, Mouse

1: 1000-1: 2000

breast, testis, brain, kidney




Background


Histone H4 H4 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H4 is involved with the structure of the nucleosome of the 'beads on a string' organization. Histone proteins are highly post-translationally modified. Covalently bonded modifications includeacetylation and methylation of the N-terminal tails. These modifications may alter expression of genes located on DNA associated with its parent histone octamer.[1][2] Histone H4 is an important protein in the structure and function of chromatin, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.




Images



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Immunohistochemistry analysis of paraffin-embedded human tonsil using Histone H4 (GB11508) at dilution of 1:1000.

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Immunohistochemistry analysis of paraffin-embedded human lung cancer using Histone H4 (GB11508) at dilution of 1:1000.

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Immunohistochemistry analysis of paraffin-embedded human liver cancer using Histone H4 (GB11508) at dilution of 1:1000.

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Immunohistochemistry analysis of paraffin-embedded human colon using Histone H4(GB11508) at dilution of 1:1000.

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Immunohistochemistry analysis of paraffin-embedded human colon cancer using Histone H4(GB11508) at dilution of 1:1000.

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Immunohistochemistry analysis of paraffin-embedded human lymphoma using Histone H4(GB11508) at dilution of 1:1000.

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Immunohistochemistry analysis of paraffin-embedded human breast using Histone H4(GB11508) at dilution of 1:1000.

Immunofluorescent analysis of paraformaldehyde-fixed human breast using Histone H4(GB11508) at dilution of 1:1000.
Immunofluorescent analysis of paraformaldehyde-fixed mouse testis using Histone H4(GB11508) at dilution of 1:1000.
Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using Histone H4(GB11508) at dilution of 1:1000.
Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using Histone H4(GB11508) at dilution of 1:1000.




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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