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GB11515 Anti -c-Jun Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Human c-Jun.
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11515
  • Servicebio

Description

Product Information


Description

c-Jun rabbit polyclonal

Protein full name

Transcription factor AP-1

Synonyms

JUN, AP-1, AP1, c-Jun, Jun proto-oncogene, AP-1 transcription factor subunit, p39, Activator protein 1, Proto oncogene c Jun, JUNC

Immunogen

KLH conjugated Synthetic peptide corresponding to Human c-Jun.

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P05412, P05627, P17325




Applications


applications

species

dilution

Positive tissue

IHC

Human,

Mouse, Rat

1: 1000-1: 2000

kidney, lung

IF

Mouse, Rat

1: 1000-1: 2000

ovary, pancreas, bone




Background


c-Jun in combination with c-Fos, forms the AP-1 early response transcription factor. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function. It is known that c-jun plays a role in cellular proliferation and apoptosis of the endometrium throughout the menstrual cycle. The cyclic change of the c-jun protein levels is significant in the proliferation and apoptosis of glandular epithelial cells. The persistent stromal expression of c-jun protein may prevent stromal cells from entering into apoptosis during the late secretory phase




Images



Immunohistochemistry analysis of paraffin-embedded human kidney using c-Jun (GB11515) at dilution of 1:2000

Immunohistochemistry analysis of paraffin-embedded mouse kidney using c-Jun (GB11515) at dilution of 1:2000

Immunohistochemistry analysis of paraffin-embedded rat lung using c-Jun (GB11515) at dilution of 1:2000


Immunofluorescent analysis of paraformaldehyde-fixed mouse ovary using c-Jun (GB11515) at dilution of 1:1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse pancreas using c-Jun (GB11515) at dilution of 1:1000


Immunofluorescent analysis of paraformaldehyde-fixed rat bone using c-Jun (GB11515) at dilution of 1:1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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