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GB11516 Anti -RhoA + RhoC Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse RhoA .
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11516
  • Servicebio

Description

Product Information


Description

RhoA + RhoC rabbit polyclonal

Protein full name

Transforming protein RhoA

Synonyms

RhoA, ARH12, ARHA, RHO12, RHOH12,

ras homolog family member A, ARH9, H9, Rho-related GTP-binding protein RhoC

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse RhoA .

Isotype

IgG

Purity

Affinity purification

Predicted MW.

22 KDa

Observed MW.

22 KDa

Uniprot ID

P61586, Q9QUI0, P61589




Applications


applications

species

dilution

Positive tissue

WB

Mouse, Rat

1: 500-1: 1000

lung, kiney




Background


Ras homolog gene family, member A (RhoA) is a small GTPase protein in the Rho family. RhoA is primarily involved in these activities: actin organization, myosin contractility, cell cycle maintenance, cellular morphological polarization, cellular development and transcriptional control. There are many molecules can stimulate RhoA, such as  NgR1, LINGO1, p75, TROY and other unknown receptors (e.g. by CSPGs). The

activated RhoA stimulates ROCK (RhoA kinase), which stimulates LIM kinase, which then stimulates cofilin, which effectively reorganizes the actin cytoskeleton of the cell.




Images



GB11516.jpg

Western blot analysis of RhoA + RhoC (GB11516) at dilution of 1: 600.

Lane 1: Mouse lung tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Rat lung tissue lysate

Lane 4: Rat kidney tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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