PHONE

+86(027) 5111 3188

Share to:

GB11545 Anti -FAK PTK2 FADK FAK FRNK Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse  FAK
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11545
  • Servicebio

Description

Product Information


Description

FAK rabbit polyclonal

Protein full name

Focal adhesion kinase 1

Synonyms

PTK2, FADK, FAK, FAK1, FRNK, PPP1R71,

p125FAK, pp125FAK, protein tyrosine kinase 2

Immunogen

Recombinant protein corresponding to Mouse  FAK

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Plasma membrane, Cytoskeleton

Uniprot ID

Q05397, P34152, O35346




Applications


applications

species

dilution

Positive tissue

IHC

Human, Mouse, Rat

1: 1000

tonsil, lung cancer, colon cancer, heart, brain

IF

Mouse, Rat

1: 1000-1: 2000

brain, ovary, lung, heart




Background


FAK is a protein of 125 kD recruited as a participant in focal adhesion dynamics between cells, and has a role in motility and cell survival. FAK is a highly conserved, non-receptor tyrosine kinase originally identified as a substrate for the oncogene protein tyrosine kinase v-src. This cytosolic kinase has been implicated in diverse cellular roles including cell locomotion, mitogen response and cell survival. FAK is typically located at structures known as focal adhesions, which are multi-protein structures that link the extracellular matrix (ECM) to the cytoplasmic cytoskeleton.




Images



1555380173867907.png

Immunohistochemistry analysis of paraffin-embedded human tonsil using FAK (GB11545) at dilution of 1:1000

1555380182942396.png

Immunohistochemistry analysis of paraffin-embedded human lung cancer using FAK (GB11545) at dilution of 1:1000

1555380189106731.png

Immunohistochemistry analysis of paraffin-embedded human colon cancer using FAK (GB11545) at dilution of 1:1000

1555380202609114.png

Immunohistochemistry analysis of paraffin-embedded human breast  cancer using FAK (GB11545) at dilution of 1:1000

1555380215133282.png

Immunohistochemistry analysis of paraffin-embedded mouse heart using FAK (GB11545) at dilution of 1:1000

1555380291696254.png

Immunohistochemistry analysis of paraffin-embedded rat brain using FAK (GB11545) at dilution of 1:1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using FAK (GB11545) at dilution of 1:1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse ovary using FAK (GB11545) at dilution of 1:1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using FAK (GB11545) at dilution of 1:1000

Immunofluorescent analysis of paraformaldehyde-fixed rat heart using FAK (GB11545) at dilution of 1:1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.