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GB11547 IHC IF Anti -ErbB2 TKR1 NGL Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse ErbB2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11547
  • Servicebio

Description

Product Information


Description

ErbB2 rabbit polyclonal

Protein full name

Receptor tyrosine-protein kinase erbB-2

Synonyms

ERBB2, CD340, HER-2, HER-2/neu, HER2,

MLN 19, NEU, NGL, TKR1, Erb-b2 receptor tyrosine kinase 2

Immunogen

Recombinant protein corresponding to Mouse ErbB2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus, Cell membrane

Uniprot ID

P04626




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 500-1: 1000

colon

IF

Human

1: 500-1: 1000

colon




Background


Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent) or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene. ERBB is abbreviated from erythroblastic oncogene B, a gene isolated from avian genome. It is also frequently called HER2 (from human epidermal growth factor receptor 2) or HER2/neu. HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded human colon

using ErbB2 (GB11547) at dilution of

1: 500

image.png

Immunohistochemistry analysis of paraffin-embedded human colon

using ErbB2 (GB11547) at dilution of

1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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