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GB11551 Anti -cPLA2 PLA2G4A PLA2G4 Alpha Rabbit PAb Antibody

Immunogen: Recombinant protein corresponding to Mouse cPLA2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11551
  • Servicebio

Description

Product Information


Description

cPLA2 rabbit polyclonal

Protein full name

Cytosolic phospholipase A2

Synonyms

PLA2G4A, PLA2G4, cPLA2-alpha, cPLA2, Phospholipase A2 group IVA

Immunogen

Recombinant protein corresponding to Mouse cPLA2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

85 kDa

Observed MW.

85 kDa

Subcellular location

Cytoplasm

Uniprot ID

P47712, P47713, P50393




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse,Rat

1: 500-1: 1000

liver, spleen, lung

IHC

Rat

1: 500-1: 1000

lung, liver

IF

Mouse, Rat

1: 500-1: 1000

Inflammatory lung, Inflammatory skin, spleen, Inflammatory liver, bone




Background


This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor.




Images



image.png

Western blot analysis of cPLA2 (GB11551) at dilution of 1: 1000.

Lane 1:A549 cell lysate

Lane 2:293T cell lysate

Lane 3:NIH/3T3 cell lysate

Lane 4:Mouse liver tissue lysate

Lane 5:Mouse spleen tissue lysate

Lane 6:Mouse lung tissue lysate

Lane 7:Rat liver tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using cPLA2 (GB11551) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat liver using cPLA2 (GB11551) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse Inflammatory lung using cPLA2 (GB11551) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse Inflammatory skin using cPLA2 (GB11551) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using cPLA2 (GB11551) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat Inflammatory liver using cPLA2 (GB11551) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat bone using cPLA2 (GB11551) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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