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GB11558 Anti -HDAC6 CPBHM CPBHM PPP1R90 JM21 Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse HDAC6
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11558
  • Servicebio

Description

Product Information


Description

HDAC6 rabbit polyclonal

Protein full name

Histone deacetylase 6

Synonyms

HDAC6, CPBHM, HD6, PPP1R90, JM21, Histone deacetylase 6

Immunogen

Recombinant protein corresponding to Mouse HDAC6

Isotype

IgG

Purity

Affinity purification

Predicted MW.

131 kDa

Observed MW.

131 kDa

Uniprot ID

Q9UBN7, Q9Z2V5




Applications


applications

species

dilution

Positive tissue

WB

Human

1: 500-1: 1000

HepG2, MCF7, HCT116




Background


Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.




Images



1533177090121491.png

Western blot analysis of HDAC6 (GB11558) at dilution of 1: 800.

Lane 1: HepG2 cell lysate

Lane 2: MCF7 cell lysate

Lane 3: HCT116 cell lysate

Lane 4: Mouse lung tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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