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GB11560 Anti -ERK1 ERK2 Rabbit PAb Antibody for WB

Immunogen:  KLH conjugated Synthetic peptide corresponding to Mouse ERK1 + ERK2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11560
  • Servicebio

Description

Product Information


Description

ERK1 + ERK2 rabbit polyclonal

Protein full name

Mitogen-activated protein kinase 3/ Mitogen-activated protein kinase 1

Synonyms

MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, P44-ERK1, P44-MAPK, Mitogen-activated protein kinase 3, MAPK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ERK1 + ERK2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

42/44 kDa

Observed MW.

42/44 kDa

Uniprot ID

P27361, P21708, Q63844,

P28482, P63086, P63085




Applications


applications

species

dilution

positive tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

liver, lung, brain




Background


Mitogen-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPK3 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Pharmacological inhibition of ERK1/2 restores GSK3β activity and protein synthesis levels in a model of tuberous sclerosis.




Images



1540964850861410.jpg

Western blot analysis of ERK1 + ERK2

(GB11560) at dilution of 1: 1000.

Lane 1: HepG2 cell lysate

Lane 2: MCF7 cell lysate

Lane 3: A549 cell lysate

Lane 4: Mouse liver tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat liver tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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