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GB11561 Anti -GABA A Receptor Alpha 1 ECA4 EJM Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse GABA A Receptor alpha 1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11561
  • Servicebio

Description

Product Information


Description

GABA A Receptor alpha 1 rabbit polyclonal

Protein full name

Gamma-aminobutyric acid receptor subunit alpha-1

Synonyms

GABRA1, ECA4, EIEE19, EJM, EJM5, Gamma-aminobutyric acid type A receptor alpha1 subunit

Immunogen

Recombinant protein corresponding to

Mouse GABA A Receptor alpha 1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot ID

P14867




Applications


applications

species

dilution

positive tissue

WB

Human

1: 500-1: 1000

U87, U251, SH-SY5Y




Background


Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.




Images



1534945580497920.png

Western blot analysis of GABA A Receptor alpha 1 (GB11561) at dilution of 1: 800.

Lane 1: U87 cell lysate

Lane 2: U251 cell lysate

Lane 3: SH-SY5Y cell lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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