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GB11570 Anti -CDC42 CDC42Hs G25K Rabbit Polyclonal Antibody for IHC IF

Immunogen: Recombinant protein corresponding to Mouse CDC42
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11570
  • Servicebio

Description

Product Information


Description

CDC42 rabbit polyclonal

Protein full name

Cell division control protein 42 homolog

Synonyms

CDC42, CDC42Hs, G25K, TKS, Cell division cycle 42, G25K, G25K GTP binding protein, Growth regulating protein, GTP binding protein 25kD, Small GTP binding protein CDC42

Immunogen

Recombinant protein corresponding to

Mouse CDC42

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoskeleton

Uniprot ID

P60953, P60766




Applications


applications

species

dilution

positive tissue

IHC

Human

1: 500-1: 1000

epityphlon, stomach

IF

Human, Mouse

1: 1000-1: 2000

liver, testis




Background


Cell division control protein 42 homolog, also known as Cdc42, is a protein involved in regulation of the cell cycle. Human Cdc42 is a small GTPase of the Rho family, which regulates signaling pathways that control diverse cellular functions including cell morphology, cell migration, endocytosis and cell cycle progression. Rho GTPases are central to dynamic actin cytoskeletal assembly and rearrangement that are the basis of cell-cell adhesion and migration. Activated Cdc42 activates by conformational changes p21-activated kinases PAK1 and PAK2, which in turn initiate actin reorganization and regulate cell adhesion, migration, and invasion.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded human epityphlon using

CDC42 (GB11570) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded human stomach using

CDC42 (GB11570) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse testis using

CDC42 (GB11570) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human liver using

CDC42 (GB11570) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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