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GB11571 Anti -E2F1 Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse E2F1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11571
  • Servicebio

Description

Product Information


Description

E2F1 rabbit polyclonal

Protein full name

Transcription factor E2F1

Synonyms

E2F1, E2F-1, RBAP1, RBBP3, RBP3, E2F transcription factor 1

Immunogen

Recombinant protein corresponding to

Mouse E2F1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

Q61501, O09139




Applications


applications

species

dilution

positive tissue

IHC

Mouse, Rat

1: 500-1: 1000

brain, spinal cord

IF

Mouse, Rat

1: 1000-1: 2000

spinal cord, brain




Background


Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

E2F1 (GB11571) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using

E2F1 (GB11571) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse spinal cord using E2F1 (GB11571) at dilution of 1: 2000

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using E2F1 (GB11571) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat brain using E2F1 (GB11571) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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