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GB11576 Anti -GADD45A Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse GADD45A
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11576
  • Servicebio

Description

Product Information


Description

GADD45A rabbit polyclonal

Protein full name

Growth arrest and DNA damage-inducible protein GADD45 alpha

Synonyms

GADD45A, DDIT1, GADD45, growth arrest and DNA damage inducible alpha

Immunogen

Recombinant protein corresponding to

Mouse GADD45A

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P48317




Applications


applications

species

dilution

positive tissue

IHC

Rat

1: 500-1: 1000

testis, heart, spleen

IF

Rat

1: 500-1: 1000

testis, heart, spleen




Background


Growth arrest and DNA-damage-inducible protein GADD45 alpha is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes, the GADD45 genes, whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents (mutagens). The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded rat testis using

GADD45A (GB11576) at dilution of 1: 500

image.png

Immunohistochemistry analysis of paraffin-embedded mouse heart using

GADD45A (GB11576) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse spleen using

GADD45A (GB11576) at dilution of 1: 500





Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles

Storage Buffer

PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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