PHONE

+86(027) 5111 3188

Share to:

GB11583 Anti -CD27 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD27
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11583
  • Servicebio

Description

Product Information


Description

CD27 rabbit polyclonal

Protein full name

CD27 antigen

Synonyms

CD27, S152, S152, LPFS2, T14, TNFRSF7, Tp55, CD27 molecule

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD27

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

P26842, P41272




Applications


applications

species

dilution

positive tissue

IHC

Human

1: 500-1: 1000

tonsil

IF

Rat

1: 1000-1: 2000

Immune spleen, lymph, thymus




Background


CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.



Images



image.png

Immunohistochemistry analysis of paraffin-embedded human tonsil using

CD27 (GB11583) at dilution of 1: 1000


Immunofluorescent analysis of paraformaldehyde-fixed rat Immune spleen using CD27 (GB11583) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat lymph using

CD27 (GB11583) at dilution of 1: 1000


Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using

CD27 (GB11583) at dilution of 1: 1000





Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles

Storage Buffer

PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.