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GB11588 Anti -Bone Sialoprotein Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Bone Sialoprotein
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11588
  • Servicebio

Description

Product Information


Description

Bone Sialoprotein rabbit polyclonal

Protein full name

Bone sialoprotein 2

Synonyms

IBSP, BNSP, BSP, BSP-II, SP-II, Integrin binding sialoprotein, Bone Sialoprotein

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bone Sialoprotein

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

Q61711




Applications


applications

species

dilution

positive tissue

IHC

Mouse

1: 500-1: 1000

bone

IF

Mouse

1: 500-1: 1000

bone




Background


Bone sialoprotein (BSP) is a component of mineralized tissues such as bone, dentin, cementum and calcified cartilage. BSP is a significant component of the bone extracellular matrix and has been suggested to constitute approximately 8% of all non-collagenous proteins found in bone and cementum. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.



Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse bone using

Bone Sialoprotein (GB11588) at dilution of 1: 750





Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles

Storage Buffer

PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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