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GB11598 Anti -PKA Alpha+beta (catalytic Subunits) Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse PKA alpha+beta
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11598
  • Servicebio

Description

Product Information


Description

PKA alpha+beta (catalytic subunits) rabbit polyclonal

Protein full name

cAMP-dependent protein kinase catalytic subunit alpha

Synonyms

PRKACA, PKACA, PPNAD4, Protein kinase cAMP-activated catalytic subunit alpha, PKA C-α, PKA C, cAMP Protein Kinase Catalytic subunit, PKA alpha+beta

Immunogen

Recombinant protein corresponding to Mouse PKA alpha+beta

Isotype

IgG

Purity

Affinity purification

Predicted MW.

41 kDa

Observed MW.

41 kDa

Uniprot ID

P17612, P05132, P27791




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, testis




Background


The catalytic subunit α of protein kinase A is a key regulatory enzyme that in humans is encoded by the PRKACA gene. This enzyme is responsible for phosphorylating other proteins and substrates, changing their activity. Protein kinase A catalytic subunit (PKA Cα) is a member of the AGC kinase family (protein kinases A, G, and C), and contributes to the control of cellular processes that include glucose metabolism, cell division, and contextual memory. PKA Cα is part of a larger protein complex that is responsible for controlling when and where proteins are phosphorylated. Defective regulation of PKA holoenzyme activity has been linked to the progression of cardiovascular disease, certain endocrine disorders and cancers.




Images



image.png

Western blot analysis of PKA alpha+beta

(GB11598) at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: Jurkat cell lysate

Lane 4: NIH/3T3 cell lysate

Lane 5: PC12 cell lysate

Lane 6: Mouse liver tissue lysate

Lane 7: Mouse testis tissue lysate

Lane 8: Rat liver tissue lysate

Lane 9: Rat testis tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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