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GB11610 Anti -MCP1 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse MCP1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11610
  • Servicebio

Description

Product Information


Description

MCP1 rabbit polyclonal

Protein full name

C-C motif chemokine 2

Synonyms

CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF, C-C motif chemokine ligand 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MCP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P13500




Applications


applications

species

dilution

positive tissue

IHC

Human

1: 500-1: 1000

epityphlon, lung

IF

Human

1: 250-1: 500

epityphlon, lung




Background


The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded human epityphlon using

MCP1 (GB11610) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using

MCP1 (GB11610) at dilution of 1: 1000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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