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GB11618 Anti -TSG101 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse TSG101(N-terminal)
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11618
  • Servicebio

Description

Product Information


Description

TSG101 rabbit polyclonal

Protein full name

Tumor susceptibility gene 101 protein

Synonyms

TSG101(N-terminal), TSG10, VPS23, tumor susceptibility 101

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TSG101(N-terminal)

Isotype

IgG

Purity

Affinity purification

Predicted MW.

44 kDa

Observed MW.

46 kDa

Uniprot ID

Q61187, Q99816, Q6IRE4




Applications


applications

species

dilution

positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, lung, brain




Background


The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression




Images



1内页.jpg

Western blot analysis of TSG101 (GB11618)

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: MCF7 cell lysate

Lane 4: Mouse liver tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat liver tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat brain tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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