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GB11631 Anti -PAK1 Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse PAK1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11631
  • Servicebio

Description

Product Information


Description

PAK1 rabbit polyclonal

Protein full name

Serine/threonine-protein kinase PAK 1

Synonyms

PAK1, PAKalpha, p21 (RAC1) activated kinase 1

Immunogen

Recombinant protein corresponding to Mouse PAK1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

61 kDa

Observed MW.

61 kDa

Uniprot ID

O88643, P35465




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 1000-1: 2000

brain, hippocampus, cortex, cerebellum




Background


PAK1 is one of six members of the PAK family of serine/threonine kinases which are broadly divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7). PAK1 localizes in distinct sub-cellular domains in the cytoplasm and nucleus which regulates cytoskeleton remodeling, phenotypic signaling and gene expression, and affects a wide variety of cellular processes such as directional motility, invasion, metastasis, growth, cell cycle progression, angiogenesis. PAK1-signaling dependent cellular functions regulate both physiologic and disease processes, including cancer, as PAK1 is widely over expressed and hyperstimulated in human cancer, at-large.




Images



2.jpg

Western blot analysis of PAK1 (GB11631)

at dilution of 1:1000

Lane 1: SH-SY5Y cell lysate

Lane 2: NIH/3T3 cell lysate

Lane 3: PC12 cell lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse cortex tissue lysate

Lane 6: Mouse hippocampus tissue lysate

Lane 7: Mouse cerebellum tissue lysate

Lane 8: Rat brain tissue lysate

Lane 9: Rat cortex tissue lysate

Lane 10: Rat hippocampus tissue lysate

Lane 11: Rat cerebellum tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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