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Anti -Chk1 Rabbit PAb for Western Blot Antibodies

Specification: 100uL
  • GB11633
  • Servicebio
  • Servicebio

Description

Product Information


Description

Chk1 rabbit polyclonal

Protein full name

Serine/ threonine-protein kinase Chk1

Synonyms

CHEK1, Chk1, checkpoint kinase 1

Immunogen

Recombinant protein corresponding to Mouse Chk1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

45 kDa

Observed MW.

45 kDa

Uniprot ID

O14757, O35280, Q91ZN7




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, lung




Background


Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that are involved in cell cycle control. Two checkpoint kinase subtypes have been identified, Chk1 and Chk2. Chk1 is a central component of genome surveillance pathways and is a key regulator of the cell cycle and cell survival. Chk1 is required for the initiation of DNA damage checkpoints and has recently been shown to play a role in the normal (unperturbed) cell cycle. Chk1 impacts various stages of the cell cycle including the S phase, G2/M transition and M phase. In addition to mediating cell cycle checkpoints, Chk1 also contributes to DNA repair processes, gene transcription, embryo development, cellular responses to HIV infection and somatic cell viability.




Images



2.jpg

Western blot analysis of Chk1 (GB11633)

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: Mouse spleen tissue lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Rat spleen tissue lysate

Lane 6: Rat lung tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

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