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Anti -CDK1 Rabbit pAb Western Blot Antibodies

Specification: 100uL
  • GB11635
  • Servicebio
  • Servicebio

Description

Product Information


Description

CDK1 rabbit polyclonal

Protein full name

Cyclin-dependent kinase 1

Synonyms

CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1

Immunogen

Recombinant protein corresponding to Mouse CDK1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

34 kDa

Observed MW.

34 kDa

Uniprot ID

P06493, P11440, P39951




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 2000

spleen, thymus




Background


Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.




Images



2.jpg

Western blot analysis of CDK1 (GB11634)

at dilution of 1: 800

Lane 1: A549 cell lysate

Lane 2: MCF7 cell lysate

Lane 3: NIH/3T3 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse thymus tissue lysate

Lane 6: Rat spleen tissue lysate

Lane 7: Rat thymus tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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