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Anti -Bim Rabbit PAb for Western Blot Protein Detection Antibody

Specification: 100uL
  • GB11638
  • Servicebio
  • Servicebio

Description

Product Information


Description

Bim rabbit polyclonal

Protein full name

Bcl-2-like protein 11

Synonyms

BCL2L11, BAM, BiM, BOD, BCL2 like 11

Immunogen

Recombinant protein corresponding to Mouse Bim

Isotype

IgG

Purity

Affinity purification

Predicted MW.

22 kDa

Observed MW.

22 kDa

Uniprot ID

O43521, O54918, O88498




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, lung, thymus




Background


Bcl-2-like protein 11, commonly called BIM, is a protein that in humans is encoded by the BCL2L11 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1 (FoxO3a), which suggests a role of this gene in neuronal and lymphocyte apoptosis.




Images



2.jpg

Western blot analysis of Bim (GB11638)

at dilution of 1: 800

Lane 1: Jurkat cell lysate

Lane 2: Raw264.7 cell lysate

Lane 3: A20 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse thymus tissue lysate

Lane 7: Rat spleen tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat thymus tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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