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Anti -Crk P38 Rabbit PAb for Western Blot Antibody Tumor Markers

Specification: 100uL
  • GB11645
  • Servicebio
  • Servicebio

Description

Product Information


Description

Crk p38 rabbit polyclonal

Protein full name

Adapter molecule crk

Synonyms

CRK, Crk p38, CRK isoform 2, CrkII; CRKII; p38, Proto oncogene C crk, v crk sarcoma virus CT10 oncogene homolog, Adapter molecule crk, Avian sarcoma virus CT10 (v crk) oncogene homolog, Adapter molecule crk

Immunogen

Recombinant protein corresponding to Human Adapter molecule crk

Isotype

IgG

Purity

Affinity purification

Predicted MW.

34 kDa

Observed MW.

38 kDa

Uniprot ID

P46108




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

HepG2, A549, MCF7,

293T, U87




Background


Adapter molecule crk also known as proto-oncogene c-Crk or p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.




Images




2.jpg

Western blot analysis of Adapter molecule

Crk (GB11645) at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: A549 cell lysate

Lane 3: MCF7 cell lysate

Lane 4: 293T cell lysate

Lane 5: U87 cell lysate






Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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