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Anti -NFkB P100 / P52 Rabbit PAb for Western Blot Polyclonal Antibody

Specification: 100uL
  • GB11651
  • Servicebio
  • Servicebio

Description

Product Information


Description

NFkB p100 / p52 rabbit polyclonal

Protein full name

Nuclear factor NF-kappa-B p100 subunit

Synonyms

NFKB2, CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52, p100, p49/p100, nuclear factor kappa B subunit 2, NF-κB, Nuclear factor NF-kappa-B p100 subunit

Immunogen

Recombinant protein corresponding to Human Nuclear factor NF-kappa-B p100 subunit

Isotype

IgG

Purity

Affinity purification

Predicted MW.

97 kDa

Observed MW.

100 kDa

Uniprot ID

Q00653




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 1000-1: 2000

HeLa, Jurkat, MCF7




Background


NF-κB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-κB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.




Images



2.jpg

Western blot analysis of NFkB p100

(GB11651) at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: Jurkat cell lysate

Lane 3: MCF7 cell lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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