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Anti -SMAD6 Rabbit PAb for IHC IF Primary Antibody

Specification:100uL
  • GB11654
  • Servicebio
  • Servicebio

Description


Product Information


Description

SMAD6 rabbit polyclonal

Protein full name

Mothers against decapentaplegic homolog 6

Synonyms

SMAD6, AOVD2, HsT17432, MADH6, MADH7, SMAD family member 6

Immunogen

Recombinant protein corresponding to Mouse SMAD6

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

O35182




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1000

brain, heart, lung

IF

Mouse, Rat

1: 250-1: 500

brain, heart, lung




Background


SMAD family member 6, also known as SMAD6, belongs to the SMAD family of proteins, which belong to the TGFβ superfamily of modulators. Like many other TGFβ family members SMAD6 is involved in cell signalling. It acts as a regulator of TGFβ family (such as bone morphogenetic proteins) activity by competing with SMAD4 and preventing the transcription of SMAD4's gene products. There are two known isoforms of this protein.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

SMAD6 (GB11654) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded rat heart using

SMAD6 (GB11654) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using

SMAD6 (GB11654) at dilution of 1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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