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Anti -Hexokinase 1 Rabbit PAb Glucose Metabolism Western Blot Antibody

Specification:100uL
  • GB11657
  • Servicebio
  • Servicebio

Description

Product Information


Description

Hexokinase 1 rabbit polyclonal

Protein full name

Hexokinase-1

Synonyms

HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, Hexokinase 1, HK, hexokinase, RP79

Immunogen

Recombinant protein corresponding to

Mouse Hexokinase 1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

108 kDa

Observed MW.

108 kDa

Uniprot ID

P19367, P17710, P05708




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, muscle, brain




Background


Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6-phosphate (G6P), the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria to make sure the sufficient energy production by accelerating the cycle of glucose metabolism pathways. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster.




Images



2.jpg

Western blot analysis of Hexokinase 1

(GB11657) at dilution of 1: 1000

Lane 1: MCF7 cell lysate

Lane 2: 293T cell lysate

Lane 3: U87 cell lysate

Lane 4: Mouse heart tissue lysate

Lane 5: Mouse muscle tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat heart tissue lysate

Lane 8: Rat muscle tissue lysate

Lane 9: Rat brain tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

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