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Anti -Ionotropic Glutamate receptor 2 Rabbit pAb for IHC IF

Specification:100uL
  • GB11666
  • Servicebio
  • Servicebio

Description

Product Information


Description

Ionotropic Glutamate receptor 2 rabbit polyclonal

Protein full name

Glutamate receptor 2

Synonyms

Gria2, GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, Glutamate ionotropic receptor AMPA type subunit 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GLUR2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membran, Cytoplasm

Uniprot ID

P23819




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 1000-1: 2000

spinal cord

IF

Mouse

1: 500-1: 1000

spinal cord




Background


Glutamate ionotropic receptor AMPA type subunit 2 (ionotropic glutamate receptor 2) is a protein that in humans is encoded by the GRIA2 (or GLUR2) gene. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+).



Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using

GLUR2 (GB11666) at dilution of 1: 1500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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