PHONE

+86(027) 5111 3188

Share to:

Anti -Calcineurin A Rabbit PAb Western Blot Antibody

Specification:100uL
  • GB11669
  • Servicebio
  • Servicebio

Description

Product Information


Description

Calcineurin A rabbit polyclonal

Protein full name

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

Synonyms

Ppp3ca, PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B, protein phosphatase 3 catalytic subunit alpha, IECEE, IECEE1,  Calcineurin A

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Calcineurin A

Isotype

IgG

Purity

Affinity purification

Predicted MW.

59 kDa

Observed MW.

59 kDa

Uniprot ID

Q08209, P63328, P63329




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

heart, spleen, brain




Background


Calcineurin, a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. This metalloenzyme, also known as phosphatase 2B, is a heterodimer composed of a calmodulin binding, catalytic alpha subunit 61 kDa, calcineurin A) and calcium binding beta subunit (18 kDa, calcineurin B). The Ca2+ binding subunit, calcineurin B, is immunologically conserved from yeast to mammals. The presence of 2 different calcineurin B isoforms (beta 1 and beta 2) has been reported in rat testis. The catalytic subunit of calcineurin, calcineurin A, isolated from different tissues or different organisms, exhibits some immunological heterogeneity.



Images



内页.jpg

Western blot analysis of Calcineurin A

(GB11669) at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: A549 cell lysate

Lane 3: SH-SY5Y cell lysate

Lane 4: Mouse heart tissue lysate

Lane 5: Mouse spleen tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat heart tissue lysate

Lane 8: Rat spleen tissue lysate

Lane 9: Rat brain tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.