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Anti -Smoothened Rabbit PAb Western Blot Antibody

Specification:100uL
  • GB11670
  • Servicebio
  • Servicebio

Description

Product Information


Description

Smoothened rabbit polyclonal

Protein full name

Smoothened homolog

Synonyms

Smo, SMO, FZD11, Gx, SMOH, Smoothened, frizzled class receptor, CRJS

Immunogen

Recombinant protein corresponding to Mouse Smoothened

Isotype

IgG

Purity

Affinity purification

Predicted MW.

87 kDa

Observed MW.

87 kDa

Uniprot ID

P56726, P97698




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, cerebral cortex,

cerebellum, hippocampus




Background


Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a Class Frizzled (Class F) G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the natural teratogen cyclopamine. It also is the target of Vismodegib, the first hedgehog pathway inhibitor to be approved by the U.S. Food and Drug Administration (FDA).



Images



内页.jpg

Western blot analysis of Smoothened

(GB11670) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse cerebellum tissue lysate

Lane 3: Mouse cerebral cortex tissue lysate

Lane 4: Mouse hippocampus tissue lysate

Lane 5: Rat brain tissue lysate

Lane 6: Rat cerebellum tissue lysate

Lane 7: Rat cerebral cortex tissue lysate

Lane 8: Rat hippocampus tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

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