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Anti -Sarcomeric Alpha Actinin Rabbit pAb for WB western blot antibody

Specification:100uL
  • GB11674
  • Servicebio
  • Servicebio

Description

Product Information


Description

Sarcomeric Alpha Actinin rabbit polyclonal

Protein full name

Alpha-actinin-2

Synonyms

ACTN2, CMD1AA, CMH23, Actinin alpha 2, Actn2, Sarcomeric Alpha Actinin

Immunogen

Recombinant protein corresponding to Mouse Sarcomeric Alpha Actinin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

104 kDa

Observed MW.

104 kDa

Uniprot ID

Q9JI91




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 1000-1: 2000

lung, colon,

stomach, muscle




Background


Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal and cardiac muscles and functions to anchor myofibrillar actin thin filaments and titin to Z-discs. The primary function of alpha-actinin 2 is to crosslink filamentous actin molecules and titin molecules from adjoining sarcomeres at Z-discs, a function that is modulated by phospholipids. Alpha-actinin 2 also functions in docking signalling molecules at Z-discs, and additional studies have also implicated alpha-actinin 2 in the binding of cardiac ion channels, Kv1.5 in particular.




Images



内页.jpg

Western blot analysis of Sarcomeric Alpha Actinin (GB11674) at dilution of 1: 1000

Lane 1: Mouse lung tissue lysate

Lane 2: Mouse colon tissue lysate

Lane 3: Mouse stomach tissue lysate

Lane 4: Mouse muscle tissue lysate

Lane 5: Rat lung tissue lysate

Lane 6: Rat colon tissue lysate

Lane 7: Rat stomach tissue lysate

Lane 8: Rat muscle tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

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