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Anti -Munc13-1 Rabbit PAb Vesicle Transport Research Western Blot Antibody

Specification:100uL
  • GB11679
  • Servicebio
  • Servicebio

Description

Product Information


Description

Munc13-1 rabbit polyclonal

Protein full name

Protein unc-13 homolog A

Synonyms

Unc13a, UNC13A, Munc13-1, unc-13 homolog A (C. elegans), unc-13 homolog A, KIAA1032, Munc 13, Protein unc-13 homolog A, UN13A, Unc13h1

Immunogen

Recombinant protein corresponding to Mouse Munc13-1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

194 kDa

Observed MW.

194 kDa

Uniprot ID

Q4KUS2, Q62768




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 1000-1: 2000

neonatal brain




Background


Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene.. This gene encodes a member of the UNC13 family. UNC13A plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool. It is particularly important in most glutamatergic-mediated synapses but not GABA-mediated synapses. It plays a role in dendrite formation by melanocytes and in secretory granule priming in insulin secretion.



Images



内页.jpg

Western blot analysis of Munc13-1

(GB11679) at dilution of 1: 1000

Lane 1: Human brain tissue lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse neonatal brain tissue lysate

Lane 4: Rat brain tissue lysate

Lane 5: Rat neonatal brain tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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