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Anti -Macrophage Inflammatory Protein 1 Alpha / CCL3 Rabbit PAb for IHC IF

Specification:100uL
  • GB11687
  • Servicebio
  • Servicebio

Description

Product Information


Description

CCL3 rabbit polyclonal

Protein full name

C-C motif chemokine 3

Synonyms

Ccl3, CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3, C-C motif chemokine ligand 3, Macrophage Inflammatory Protein 1 alpha, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CCL3

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P10855




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 400-1: 800

spleen

IF

Mouse

1: 200-1: 400

spleen




Background


CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5. CCL3 has been shown to interact with CCL4, and attracts macrophages, monocytes and neutrophils. CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumor necrosis factor or recombinant human interleukin-1.



Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse spleen using

CCL3 (GB11687) at dilution of 1: 400





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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