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Anti -AKT1 Rabbit PAb For Western Blot Primary Antibody

Specification:100uL
  • GB111114
  • Servicebio
  • Servicebio

Description

Product Information


Description

AKT1 rabbit polyclonal

Protein full name

v-akt murine thymoma viral oncogene homolog 1

Synonyms

AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT serine/threonine kinase 1

Immunogen

Recombinant protein corresponding to Mouse AKT1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

56 kDa

Observed MW.

60 kDa

Uniprot ID

P31749, P31750, P47196




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 1500

pneumonia, splenitis,

thymus




Background


RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases. It is commonly referred to as PKB, or by both names as "Akt/PKB". The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.




Images



内页-1.jpg

Western blot analysis of AKT1 (GB11689)

at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: HeLa cell lysate

Lane 3: Raw264.7 cell lysate

Lane 4: Mouse pneumonia tissue lysate

Lane 5: Mouse splenitis tissue lysate

Lane 6: Mouse thymus tissue lysate

Lane 7: Rat pneumonia tissue lysate

Lane 8: Rat splenitis tissue lysate

Lane 9: Rat thymus tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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