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Anti -Bax Rabbit PAb for Western Blot Antibody

Specification:100UL
  • GB11007
  • Servicebio
  • Servicebio

Description

Product Information


Description

Bax rabbit polyclonal

Protein full name

Apoptosis regulator BAX

Synonyms

BAX, BCL2L4, BCL2 associated X protein, BCL2 associated X, apoptosis regulator,

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bax

Isotype

IgG

Purity

Affinity purification

Predicted MW.

21 kDa

Observed MW.

21 kDa

Uniprot ID

Q07812, Q07813, Q63690




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, pneumonia




Background


Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.




Images



内页-1.jpg

Western blot analysis of Bax (GB11690)

at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: HeLa cell lysate

Lane 3: NIH/3T3 cell lysate

Lane 4: Raw264.7 cell lysate

Lane 5: PC12 cell lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Rat pneumonia tissue lysate

Lane 8: Rat lung tissue lysate













Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles

Storage Buffer

PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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