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Anti -MEF2C Rabbit PAb for IHC IF Polyclonal Antibody

Specification:100uL
  • GB11692
  • Servicebio
  • Servicebio

Description

Product Information


Description

MEF2C rabbit polyclonal

Protein full name

Myocyte-specific enhancer factor 2C

Synonyms

Mef2c, MEF2C, C5DELq14.3, DEL5q14.3, myocyte enhancer factor 2C

Immunogen

Recombinant protein corresponding to Mouse MEF2C

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

Q06413, Q8CFN5, A0A096MJY4




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1000

skeletal muscle, brain

cardiac muscle, cerebral infarction

IF

Mouse, Rat

1: 250-1: 500

skeletal muscle, brain

cardiac muscle,

cerebral infarction




Background


Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. May also be involved in neurogenesis and in the development of cortical architecture.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded Rat skeletal muscle

using MEF2C (GB11692) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded Rat cardiac muscle

using MEF2C (GB11692) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

MEF2C (GB11692) at dilution of 1: 1000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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