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Anti -Corticotropin Releasing Factor Rabbit PAb for Western Blot Polyclonal Antibody

Specification: 100uL
  • GB11706
  • Servicebio
  • Servicebio

Description

Product Information


Description

Corticotropin Releasing Factor rabbit polyclonal

Protein full name

Corticoliberin

Synonyms

Crh, CRH, CRF, CRH1, corticotropin releasing hormone, Corticotropin Releasing Factor

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Corticotropin Releasing Factor

Isotype

IgG

Purity

Affinity purification

Predicted MW.

21 kDa

Observed MW.

26 kDa

Uniprot ID

P06850, Q8CIT0, P01143




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, hippocampus

cerebral cortex




Background


Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in the stress response. It is a releasing hormone that belongs to corticotropin-releasing factor family. Its main function is the stimulation of the pituitary synthesis of ACTH, as part of the HPA Axis. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Increased CRH production has been observed to be associated with Alzheimer's disease and major depression, and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia.




Images



内页.jpg

Western blot analysis of Corticotropin

Releasing Factor (GB11706)

at dilution of 1: 1000

Lane 1: SH-SY5Y cell lysate

Lane 2: U87 cell lysate

Lane 3: Human brain tissue lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse cerebral cortex tissue lysate

Lane 6: Mouse hippocampus tissue lysate

Lane 7: Rat brain tissue lysate

Lane 8: Rat cerebral cortex tissue lysate

Lane 9: Rat hippocampus tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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