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Anti -CX3CR1 Rabbit pAb for Western Blot

Specification: 100uL
  • GB11711
  • Servicebio
  • Servicebio

Description

Product Information


Description

CX3CR1 rabbit polyclonal

Protein full name

CX3C chemokine receptor 1

Synonyms

Cx3cr1, CX3CR1, CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, C-X3-C motif chemokine receptor 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CX3CR1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

40 kDa

Observed MW.

40 kDa

Uniprot ID

P49238, Q9Z0D9, P35411




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, lung, brain




Background


CX3C chemokine receptor 1 (CX3CR1) also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13) is a protein which binds the chemokine CX3CL1 (also called neurotactin or fractalkine). The fractalkine ligand CX3CL1 is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. Expression of this receptor appears to be associated with lymphocytes. CX3CR1 is also expressed by monocytes and plays a major role in the survival of monocytes. Fractalkine signaling has also recently been discovered to play a developmental role in the migration of microglia in the central nervous system to their synaptic targets, where phagocytosis and synaptic refinement occur.




Images



内页.jpg

Western blot analysis of CX3CR1

(GB11711) at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: HCT116 cell lysate

Lane 3: CaCO2 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat lung tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgSlice 13Laboratory(1)Slice 10Slice 12


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