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Anti -GABA A Receptor alpha 1 Rabbit pAb for IHC IF

Specification: 100uL
  • GB11716
  • Servicebio
  • Servicebio

Description

Product Information


Description

GABA A Receptor alpha 1 rabbit polyclonal

Protein full name

Gamma-aminobutyric acid receptor subunit alpha-1

Synonyms

Gabra1, GABRA1, ECA4, EIEE19, EJM, EJM5, gamma-aminobutyric acid type A receptor alpha1 subunit

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GABA A Receptor alpha 1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane, Secreted

Uniprot ID

P62812




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 600-1: 1500

colon, uterus

IF

Mouse

1: 300-1: 750

colon, uterus




Background


Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.




Images



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Immunohistochemistry analysis of paraffin-embedded mouse colon using

GABA A Receptor alpha 1 (GB11716) at dilution of 1: 600


image.png

Immunohistochemistry analysis of paraffin-embedded mouse colon using

GABA A Receptor alpha 1 (GB11716) at dilution of 1: 800


image.png

Immunohistochemistry analysis of paraffin-embedded mouse uterus using

GABA A Receptor alpha 1 (GB11716) at dilution of 1: 800






Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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