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Anti -GAD1 Rabbit PAb For Western Blot

Specification: 100uL
  • GB11717
  • Servicebio
  • Servicebio

Description

Product Information



Description

GAD1 rabbit polyclonal

Protein full name

Glutamate decarboxylase 1

Synonyms

Gad1, GAD1, CPSQ1, GAD, SCP, glutamate decarboxylase 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GAD1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

67 kDa

Observed MW.

67 kDa

Uniprot ID

P48318, P18088





Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, cerebral cortex,

cerebellum




Background


Glutamate decarboxylase 1 (brain, 67kDa) (GAD67), also known as GAD1, is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. This enzyme  is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.




Images



内页.jpg

Western blot analysis of GAD1 (GB11717)

at dilution of 1: 1000

Lane 1: Human brain tissue lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse cerebral cortex tissue lysate

Lane 4: Mouse cerebellum tissue lysate

Lane 5: Rat brain tissue lysate

Lane 6: Rat cerebral cortex tissue lysate

Lane 7: Rat cerebellum tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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