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Anti -NLRP1 Rabbit pAb For IHC IF Apoptosis research

Specification:100uL
  • GB11723
  • Servicebio
  • Servicebio

Description

Product Information


Description

NLRP1 rabbit polyclonal

Protein full name

NACHT, LRR and PYD domains-containing protein 1a

Synonyms

Nlrp1a, NLRP1, CARD7, CIDED, CLR17.1, DEFCAP, DEFCAP-L/S, NAC, NALP1, PP1044, SLEV1, VAMAS1, NLR family, pyrin domain containing 1, NLR family pyrin domain containing 1, MSPC, AIADK

Immunogen

Recombinant protein corresponding to Mouse NLRP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

Q2LKU9




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 500-1: 1000

spleen

IF

Mouse

1: 250-1: 500

spleen




Background


NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.




Images



内页KM脾1-8 NLRP1 227418092702 1:1000_40.0x.jpg

Immunohistochemistry analysis of paraffin-embedded mouse speen using

NLRP1 (GB11723) at dilution of 1: 1000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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