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Anti -Axin 1 Rabbit PAb for Western Blot Protein Detection Antibody

Specification: 100uL
  • GB11729
  • Servicebio
  • Servicebio

Description

Product Information


Description

Axin 1 rabbit polyclonal

Protein full name

Axin-1

Synonyms

Axin1, AXIN1, AXIN, PPP1R49, Axin 1, Axis inhibition protein 1, Axis Inhibitor 1, Protein phosphatase 1 regulatory subunit 49, Protein Fused, PPP1R49

Immunogen

Recombinant protein corresponding to Human Axin 1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

96 kDa

Observed MW.

110 kDa

Uniprot ID

O15169, O35625, O70239




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung




Background


Axin-1 encoded by the AXIN1 gene in human is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. This protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein) beta 1, glycogen synthase kinase 3 beta, protein phosphatase 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medulloblastomas.




Images



内页.jpg

Western blot analysis of Axin 1 (GB11729)

at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: HCT116 cell lysate

Lane 3: HepG2 cell lysate

Lane 4: A20 cell lysate

Lane 5: NIH/3T3 cell lysate

Lane 6: L6 cell lysate

Lane 7: PC12 cell lysate

Lane 8: Mouse lung tissue lysate

Lane 9: Rat lung tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

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