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Anti -PLCG 2 Rabbit PAb for IHC IF Primary Antibody

Specification:100uL
  • GB11733
  • Servicebio
  • Servicebio

Description

Product Information


Description

PLCG 2 rabbit polyclonal

Protein full name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

Synonyms

Plcg2, PLCG2, APLAID, FCAS3, PLC-IV, PLC-gamma-2, Phospholipase C gamma 2

Immunogen

Recombinant protein corresponding to Mouse PLCG 2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane, Cytoplasm

Uniprot ID

Q8CIH5, P24135




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 4000-1: 8000

stomach, intestine

IF

Mouse, Rat

1: 2000-1: 4000

stomach, intestine




Background


Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C-beta is regulated by heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1) and C-gamma-2 (PLCG2) enzymes are controlled by receptor tyrosine kinases. The C-gamma-1 and C-gamma-2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded Rat stomach using

PLCG 2 (GB11733) at dilution of 1: 4000


image.png

Immunohistochemistry analysis of paraffin-embedded Rat stomach using

PLCG 2 (GB11733) at dilution of 1: 8000


image.png

Immunohistochemistry analysis of paraffin-embedded Rat intestine using

PLCG 2 (GB11733) at dilution of 1: 4000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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