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Anti -CSNK2A2 Rabbit pAb Western Blot Antibodies

Specification: 100uL
  • GB11737
  • Servicebio
  • Servicebio

Description

Product Information


Description

CKII alpha prime polypeptide rabbit polyclonal

Protein full name

Casein kinase II subunit alpha

Synonyms

Csnk2a2, CSNK2A2, CK2A2, CSNK2A1, CK2alpha, Casein kinase 2 alpha 2

Immunogen

Recombinant protein corresponding to Mouse CSNK2A2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

41 kDa

Observed MW.

41 kDa

Uniprot ID

P19784, O54833




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, testis, lung




Background


Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1.




Images



image.png

Western blot analysis of CSNK2A2 (GB11737)

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: Jurkat cell lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse testis tissue lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Rat brain tissue lysate

Lane 8: Rat testis tissue lysate

Lane 9: Rat lung tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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