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Anti -IP3 receptor Rabbit pAb for WB IHC IF Polyclonal antibody

Specification: 100uL
  • GB11742
  • Servicebio
  • Servicebio

Description

Product Information


Description

IP3 receptor rabbit polyclonal

Protein full name

Inositol 1,4,5-trisphosphate receptor type 1

Synonyms

Itpr1, ITPR1, ACV, CLA4, INSP3R1, IP3R, IP3R1, PPP1R94, SCA15, SCA16, SCA29, inositol 1, 5-trisphosphate receptor type 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Human IP3 receptor

Isotype

IgG

Purity

Affinity purification

Subcellular location

Endoplasmic reticulum

Predicted MW.

313 kDa

Observed MW.

313 kDa

Uniprot ID

Q14643




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

SH-SY5Y, U87

IHC

Mouse, Rat

1: 1500-1: 3000

brain

IF

Mouse, Rat

1: 750- 1: 1500

brain




Background


Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ITPR1 gene. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.




Images



image.png

Western blot analysis of IP3 receptor (GB11742) at dilution of 1: 1000

Lane 1: SH-SY5Y cell lysate

Lane 2: U87 cell lysate

image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

IP3 receptor (GB11742) at dilution of 1: 3000


image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using

IP3 receptor (GB11742) at dilution of 1: 3000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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